This website has been produced and funded by Novo Nordisk and is intended for adult patients in

the United Kingdom who have been prescribed Wegovy®▼ (semaglutide injection). Side effect reporting

information can be found in the footer of this page.

 

Frequently asked questions

Woman on computer
This image is for illustrative purposes only and does not include a real patient.

When you start taking Wegovy®, you might have a lot of questions about your treatment. The information on this page is designed to answer some common questions about treatment with Wegovy®.

 

Remember that your healthcare team is there to answer any other questions, or discuss any concerns, that you may have. You might find it useful to write down any questions that you have so that you remember to discuss these at your next appointment.

 

How do I inject Wegovy®?

Wegovy® is given as an injection under the skin (subcutaneous injection). Do not inject into a vein or muscle. Before using the Wegovy® FlexTouch® pen for the first time, ask your doctor or nurse how to use it.

These are the best places to give the injection:

Injection site diagram

You may inject in the same body area each week, but you must make sure it is not in the same spot you used the last time. If you are on the 7.2 mg once-weekly weight management dose (three injections of 2.4 mg), the injections can be given in the same body area but should be at least 5 cm apart. If you are on the 7.2 mg dose please refer to this Dosing guide.

 

Before injecting, always check that the Wegovy® in the pen is clear and colourless and always use a new needle for each injection. For more information on how to use Wegovy®, read the Patient Information Leaflet (PIL) →

 

You can also visit the page How do I take my medicine? for more guidance on how to use the Wegovy® FlexTouch® pen, including an example video.

You should use Wegovy® once a week and, if possible, on the same day each week. You can give yourself the injection at any time of the day, regardless of meals. If you are on Wegovy® 7.2mg once-weekly maintenance dose, you will need to inject three doses of 2.4 mg, one after each other on the same day. If you need to, you can change the day of your weekly dose of Wegovy®, as long as it has been at least three days since your last dose. After selecting a new dosing day, continue with taking Wegovy® once a week.

 

Find out more about how and when to take Wegovy® on theHow do I take my medicine?section of this website.

 

Reporting side effects

 

This medicine is subject to additional monitoring. This will allow quick identification of new safety information promptly. You can help by reporting any side effects you may get. See https://yellowcard.mhra.gov.uk/ for how to report side effects.

 

If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in the package leaflet. You can also report side effects directly via the Yellow Card Scheme at https://yellowcard.mhra.gov.uk/. Side effects should also be reported to Novo Nordisk Limited (Telephone Novo Nordisk Customer Care Centre 0800 023 2573). Calls may be monitored for training purposes. By reporting side effects, you can help provide more information on the safety of this medicine.

 

A full list of side effects, warnings and precautions can be found in the Patient Information Leaflet (PIL). You can learn more about possible side effects on the ‘Safety information’ section of this website.

 

If you have taken more Wegovy® than you should, contact your healthcare professional straight away. They will be able to advise you on what to do next. You may get side effects, such as feeling sick (nausea).

 

 

Do not take a double dose to make up for a missed one. If you do miss a dose, you should follow the five-day rule:

 

  • Five days or less since you should have used Wegovy®: use it as soon as you remember, then inject your next dose as usual on your scheduled day
  • More than five days since you should have used Wegovy®: skip the missed dose and inject as usual on your next scheduled day

 

‘Dose escalation’ means that your dose will be gradually increased. This is done to help lower the chances of experiencing gastrointestinal side effects such as feeling sick (nausea) or being sick (vomiting). Your treatment will start at the lowest available dose — 0.25 mg once weekly. Your healthcare professional will gradually increase your dose every four weeks until you reach the recommended maintenance dose. Your healthcare professional will assess your treatment on a regular basis.

If you experience side effects, your healthcare professional may decide to lower to a previous dose or delay increasing your dose until your symptoms are better. It’s really important that you let them know about any side effects you experience so they can make sure you’re on the right dose. You can learn more about dose escalation by visiting the ‘How do I take my medicine?’ section of this website.

You should follow the dosing plan as prescribed by your doctor, pharmacist or nurse.

When you first start using Wegovy®, the starting dose is 0.25 mg once weekly. Your healthcare professional will instruct you to gradually increase your dose every 4 weeks until you reach the dose of 2.4 mg once weekly. If needed, for adult patients living with obesity, a dose increase to the next maintenance dose 7.2 mg once weekly (three injections of 2.4 mg) can be made after a minimum of 4 weeks on 2.4 mg. The maximum dose is 7.2 mg once weekly. This gradual titration up to the maintenance dose helps to reduce the likelihood of developing gastrointestinal side effects. This means side effects relating to your digestive system. These can include feeling or being sick, diarrhoea, constipation and stomach pain.

If you experience side effects, your healthcare professional may decide to lower to a previous dose or delay increasing your dose until your symptoms are better. It’s really important that you let them know about any side effects you experience so they can make sure you’re on the right dose.

You should follow the dosing plan as prescribed by your doctor, pharmacist or nurse.

Speak to your healthcare team about your treatment plan with Wegovy®. Your healthcare professional will assess your treatment on a regular basis as everyone’s treatment journey is personal. Your needs may be different to someone else who is on Wegovy®.


Always use this medicine exactly as your doctor has told you. Check with your doctor, pharmacist or nurse if you are not sure.

Do not stop using Wegovy® without talking to your healthcare professional.

Please contact Novo Nordisk Customer Care by clicking here or by phoning 0800 023 2573 (open 8.30am to 5.30pm weekdays and bank holidays) if you are having issues with use.

 

If you have a latex allergy, please talk to your healthcare team. They will advise you on whether you can still use Wegovy®. You can also contact Novo Nordisk Customer Care by clicking here or by phoning 0800 023 2573 (open 8.30am to 5.30pm weekdays and bank holidays).

 

Knowing how to store your medicine is important to ensure Wegovy® works properly.

  • Keep your Wegovy® pen out of the sight and reach of children
  • Do not freeze Wegovy® and do not use if it has been frozen
  • Keep the pen cap on when the pen is not in use to protect it from light
  • Do not use this medicine after the expiry date, which is stated on the pen label and carton after ‘EXP’. The expiry date refers to the last day of that month

 

Before opening: keep the pen refrigerated (2°C to 8°C). Keep the pen away from the cooling element inside the fridge.

 

During use: you can keep the pen for six weeks when stored at a temperature below 30°C or in a fridge (2°C to 8°C) away from the cooling element inside the fridge.

 

Never store your pen with the needle attached.

 

Read more about storage and disposal of Wegovy® on the ‘How do I take my medicine?’ section of this website.

 

When the pen is empty, dispose of the pen without a needle on as instructed by your doctor, pharmacist, nurse or local authorities. The pen cap and the empty carton can be disposed of in your household waste.

 

Always dispose of the needle immediately after each injection using a sharps bin. Never store your pen with the needle attached. Keep your sharps bin in a safe place so it’s not a risk to other people and is out of the sight and reach of children.

 

Sharps bins must not be disposed of in household waste. Discuss with your healthcare professional the procedure for disposing of sharps bins in your area.

 

Read more about storage and disposal of Wegovy® on the ‘How do I take my medicine?’ section of this website.

 

Please remember that needles are for single use only. You should never reuse your needles as it may lead to blocked needles, contamination, infection and inaccurate dosing.

 

Novo Nordisk also provides a pre-filled pen recycling initiative, PenCycle®. You can discover more about it here.

 

For tips on overcoming needle hesitancy, visit the How do I take my medicine? section of this website.

 

If you have poor eyesight and cannot follow the instructions for use, you should get help from a person with good eyesight who is trained to use the Wegovy® FlexTouch® pen. Caregivers must be very careful when handling used needles to prevent accidental needle stick injuries and infection. You should also watch the 'how-to-use' video on the ‘How do I take my medicine?’ section of this website.

 

Please remember that you should never share your pen or your needles with other people.

 

Consider setting an alarm on your phone to remind you to take Wegovy® while not in your normal routine. You could also ask a family member or friend to help remind you.

 

For more tips on remembering to take your treatment, visit the ‘How do I take my medicine?’ section of this website.

 

It is possible to travel with your Wegovy® FlexTouch® pen. When travelling by air, keep your pen with you or in your carry-on, as it may freeze in the baggage compartment. Be sure to check with the airline and the requirements of the destination country, to see if they have any specific baggage rules. If needed, Wegovy® may be stored for 6 weeks at a temperature below 30°C.

 

The information on this website does not replace the Patient Information Leaflet (PIL), which you are advised to read in full. It is not intended as a substitute for clinical advice provided by your healthcare professional. Please contact your healthcare professional if you have any questions about your treatment and for clinical advice. Please refer to the PIL for further information on Wegovy®, further information on how to use Wegovy® and a full list of side effects, warnings and precautions.

Reporting side effects

This medicine is subject to additional monitoring. This will allow quick identification of new safety information promptly. You can help by reporting any side effects you may get. See https://yellowcard.mhra.gov.uk/ for how to report side effects.

If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in the package leaflet. You can also report side effects directly via the Yellow Card Scheme at https://yellowcard.mhra.gov.uk/. Side effects should also be reported to Novo Nordisk Limited (Telephone Novo Nordisk Customer Care Centre 0800 023 2573). Calls may be monitored for training purposes. By reporting side effects, you can help provide more information on the safety of this medicine. 

UK26SEMO00014 | January 2026

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